Table 3.

Unsolicited Adverse Events Occurring in ≥2 Participants From Days 8–28, by Study Group

Adverse Event	Placebo Group (n = 153)	15/50 Vaccine Group (n = 145)	50/50 Vaccine (n = 154)
Any	36 (23.5)	22 (15.2)	33 (21.4)
Headache	4 (2.6)	4 (2.8)	6 (3.9)
Nausea	4 (2.6)	1 (0.7)	3 (1.9)
Myalgia	1 (0.7)	4 (2.8)	2 (1.3)
Upper abdominal pain	2 (1.3)	2 (1.4)	1 (0.6)
Back pain	2 (1.3)	2 (1.4)	1 (0.6)
Diarrhea	2 (1.3)	1 (0.7)	2 (1.3)
Oropharyngeal pain	2 (1.3)	1 (0.7)	2 (1.3)
Pain in extremities	3 (2.0)	0	2 (1.3)
Cough	1 (0.7)	1 (0.7)	2 (1.3)
Dizziness	1 (0.7)	2 (1.4)	1 (0.6)
Bruising (injection site)	3 (2.0)	1 (0.7)	0
Pain (injection site)	0	3 (2.1)	1 (0.6)
Nasopharyngitis	1 (0.7)	2 (1.4)	1 (0.6)
Sinus headache	2 (1.3)	0	2 (1.3)
Fatigue	1 (0.7)	0	2 (1.3)
Arthropod bite	1 (0.7)	0	1 (0.6)
Dysmenorrhea	1 (0.7)	1 (0.7)	0
Dyspepsia	1 (0.7)	0	1 (0.6)
Ligament sprain	0	1 (0.7)	1 (0.6)
Migraine	0	1 (0.7)	1 (0.6)
Neck pain	0	2 (1.4)	0
Rash	2 (1.3)	0	0
Allergic rhinitis	1 (0.7)	1 (0.7)	0
Tonsillitis	0	0	2 (1.3)
Urticaria	0	0	2 (1.3)

Data are no. (%) of subjects.