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. 2008 Apr 18;37(5):1148–1157. doi: 10.1093/ije/dyn065

Table 3.

Differences between sequential and combinatorial algorithm (meta-analyses with two or more excluded studies)

Different number of studies excluded (%) Different studies excluded, aiming for maximum I2 belowInline graphic (%) Different studies excluded, aiming for minimum I2 belowInline graphic (%)
Genetic meta-analyses
    50% threshold (n = 8) 0 (0) 0 (0) 1 (11.1)
    25% threshold (n = 18) 1 (5.6) 5 (27.8) 2 (11.1)
Cochrane meta-analyses
    50% threshold (n = 91) 5 (5.6) 26 (28.6) 15 (16.5)
    25% threshold (n = 215) 10 (4.7) 52 (24.2) 33 (15.3)