Table 1. Patients information and histological analysis for lung cancer patients.
| donorID | Tissue | Gender | Age | Smoking history | Spirometry parameters (% predicted) | Histopathological changes, tumour stage and grade |
|---|---|---|---|---|---|---|
| 1 | Lung | male | 76 | Previous smoker > 50y Stopped in the 1960s |
FVC 123 FEV1 132 |
Typical carcinoid tumour growing in a well-defined area. Tumour cells without necrosis or mitotic activity according to Ki67 staining. Positivity to chromogranin, synaptophysin and CD56. TTF-1 positivity in peripheral parts of the tumour. No sign of growing through pleura. |
| 2 | Lung | female | 52 | Previous smoker > 6y Stopped in 2000 |
FVC 121 FEV1 98 |
Lung adenocarcinoma, invasively growing, low differentiated. Tumour cells positive for CK7 and TTF1. CK20, CD56, chromogranin, synaptophysin and S100 staining negative. No infiltration of the pleura. |
| 3 | Lung | male | 48 | Never smoked | FVC 89 FEV1 90 |
Typical carcinoid tumour growing in a well-defined area. Positive for chromogranin, synaptophysin and CD56. TTF-positivity in the peripheral parts of the tumour. No necrotic or mitotic activity according to Ki67 staining. |
| 4 | Lung | female | 56 | Never smoked | FVC 111 FEV1 107 |
Adenocarcinoma, invasively growing. Tumour cells positive for CK-7 and TTF-1. Staining against P40, CDX2 and CK20 negative. No infiltration of the pleura. |
| 5 | Lung | female | 74 | Previous smoker > 7y Stopped in 1999 |
FVC 86 FEV1 84 |
Adenocarcinoma, 28 mm growing through pleura. No signs of malignancy. |
| 6 | Lung | male | 82 | Never smoked | FVC 101 FEV1 92 |
Typical carcinoid tumour. Positive for chromogranin, synaptophysin and CD56. Negative for TTF-1. Ki-67 staining shows low mitotic activity. |
| 7 | Colon | female | 70 | High grade adenocarcinoma T3b N2a = Stage III | ||
| 8 | Colon | female | 89 | Low grade adenocarcinoma T3b N0 = Stage II | ||
| 9 | Colon | male | 74 | High grade adenocarcinoma T4b N1b =Stage III | ||
| 10 | Colon | female | 71 | Adenoma, no cancer | ||
| 11 | Colon | female | 67 | High grade adenocarcinoma T3c N2b= Stage III | ||
| 12 | Colon | male | 76 | Low grade adenocarcinoma T4aN0 = Stage II |
Demographics for the patients included in the RNAseq study. Information include: age at diagnosis, gender, smoking history (only for lung donors), spirometry parameters (only for lung donors), histopathological changes and/or tumour histotype and grade.