Skip to main content
. Author manuscript; available in PMC: 2018 Dec 5.
Published in final edited form as: Chem Res Toxicol. 2015 Oct 28;28(11):2112–2119. doi: 10.1021/acs.chemrestox.5b00278

Table 2.

Rate of NNAL-O-Gluc formation stratified by UGT2B17 deletion genotype.a

*1/*1
 *1/*2
 *2/*2
Subject (R)-NNAL-O-Gluc (S)-NNAL-O-Gluc (R)-NNAL-O-Gluc (S)-NNAL-O-Gluc (R)-NNAL-O-Gluc (S)-NNAL-O-Gluc
1 360 1106 316 855 333 2784
2 422 747 496 928 4.8 174
3 360 593 140 1007 144 1181
Mean ± SD 380 ± 36 815 ± 263 317 ± 178 930 ± 76 161 ± 165 1380 ± 1317
a

Rate units are expressed as pmol/min/mg total HLM protein. Values shown for each HLM specimen are the mean of three independent assays.