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. 2018 Dec 5;9(12):1174. doi: 10.1038/s41419-018-1216-3

Fig. 1. miR-125b negatively regulates p53 expression and cell growth in NSCLC cells.

Fig. 1

Taqman analysis of miR-125b expression in A549 and H460 cells upon 48 h transient transfection with miR-125b mimic (up) and relative p53 protein levels measured through Western Blot assay (down).*P < 0.05, **P < 0.01 (a). Taqman analysis of miR-125b expression in A549 and H460 cells upon 48 h transient transfection with miR-125b antagomiR (up) and relative p53 protein levels measured through Western Blot assay (down) *P < 0.05, **P < 0.01 (b). MTT assay of A549 (left) and H460 (right) cell lines at 12, 24, and 48 h upon miR-125b mimic transfection. ANOVA: °P < 0.05, ns: not significant. Each assay was performed in triplicate (c). MTT assay of A549 (left) and H460 (right) cell lines at 12, 24, and 48 h upon miR-125b antagomiR transfection. ANOVA:°P < 0.05, °°P < 0.01, °°°P < 0.001, ns: not significant. Each assay was performed in triplicate (d)