Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 5;9:5198. doi: 10.1038/s41467-018-07692-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — Spatial eQTL-eGene interactions central to the fat metabolism cluster. a Transcript levels for genes located within Chr. 11: chr11:61447905–61659017 are associated with eQTLs located in clusters across the 283 kb locus. For simplicity, we grouped eQTLs according to separation in the linear sequence such that they are located in different genes, or are separated by ≤5 kb. Genomic locations are from human genome Hg19 and the eQTL-eGene interaction analysis used GTEx v4 (18/10/2016). b Phenotype-associated eQTLs are localised or dispersed across the FADS1 locus. eQTLs associated with cis-trans-18:2 fatty acid levels are the most dispersed. eQTLs rs174545-50 are associated with the most phenotypes. The regulatory region span (in bp) includes the spatial eQTL SNPs in the group. eQTL SNPs are coloured according to the putative regulatory regions in a