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. 2018 Dec 5;4:112. doi: 10.1038/s41420-018-0121-y

Table 2.

Established markers of ovarian aging and OAGS expression in genetically diverse mice

GeneSymbol GeneDescription Relative expression in C57BL/6Ja
(mean ± s.d.)
Relative expression in FVB/NJa,b
(mean ± s.d.)
Cyp19a1 Cytochrome P450, family 19, subfamily a, polypeptide 1 0.06 ± 0.012 0.033 ± 0.014
Inhba Inhibin beta-A 0.023 ± 0.074 0.103 ± 0.054
Inha Inhibin alpha 0.360 ± 0.094 0.195 ± 0.044**
Amh Anti-Mullerian hormone 0.163 ± 0.041 0.091 ± 0.029**
Gdf9 Growth differentiation factor 9 0.028 ± 0.006 0.018 ± 0.004**
Bmp15 Bone morphogenetic protein 15 0.015 ± 0.003 0.011 ± 0.003**
Gas5 Growth arrest specific 5 1.784 ± 0.310 1.589 ± 0.181
Snord16a Small nucleolar RNA, C/D box 16A 0.113 ± 0.047 0.114 ± 0.022
Snora34 Small nucleolar RNA, H/ACA box 34 1.218 ± 0.224 1.185 ± 0.296
Mir143 microRNA 143 0.006 ± 0.002 0.117 ± 0.026**
Mir145 microRNA 145 335.0 ± 189.0 2868.0 ± 562.0
Mir681 microRNA 681 0.181 ± 0.113 1.849 ± 0.402**
Mir692-1 microRNA 692-1 0.059 ± 0.029 1.877 ± 0.540**
Fshr Follicle stimulating hormone receptor 0.023 ± 0.004 0.009 ± 0.002**
Acvr1b Activin A receptor, type 1B 0.005 ± 0.001 0.007 ± 0.002

a2−∆∆Ct

bP < 0.05; **P < 0.01 relative expression in FVB/NJ/C57BL/6J *P < 0.05; **P < 0.01 relative expression in FVB/NJ/C57BL/6J