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. 2018 Dec 5;7:205. doi: 10.1038/s41426-018-0201-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Three-week-old hSCARB2 KI mice were inoculated with CMU4232/ CDV-Isehara via I.C. or I.V. route. EV-A71 genome copy numbers in the brain, heart, lung, intestine, and muscle of EV-A71-infected Tg mice were determined at several time points by quantitative RT-PCR. Mouse β-actin gene expression in each tissue was used as the internal control. Results represent the mean of three to five samples; error bars represent STDEV. a CMU4232/I.C. (N = 3); b CDV-Isehara/I.C. (N = 4); c CMU4232 /I.V. (N = 5); d CDV-Isehara/I.V. (N = 4)