Table 3.
Gender-specific facial features in acromegaly.
| Males | Females | |||||
|---|---|---|---|---|---|---|
| Acromegaly (n = 23) | Control (n = 23) | P1 value | Acromegaly (n = 16) | Control (n = 16) | P2 value | |
| NOSE-RELATED INDEXES | ||||||
| Nose length (mm) | 51.0 ± 4.75 | 45.4 ± 3.22 | <0.001 | 42.1 ± 4.41 | 41.7 ± 2.57 | 0.752 |
| Nasal depth (mm) | 21.2 ± 2.40 | 19.1 ± 1.87 | 0.002 | 19.6 ± 2.33 | 18.6 ± 1.82 | 0.202 |
| Nose height (mm) | 57.2 ± 3.77 | 52.9 ± 3.58 | <0.001 | 50.3 ± 4.68 | 50.1 ± 2.22 | 0.850 |
| Nose width (mm) | 51.2 ± 4.14 | 43.2 ± 2.30 | <0.001 | 45.6 ± 2.25 | 40.2 ± 2.50 | <0.001 |
| Nasal width index (%) | 89.8 ± 7.30 | 82.1 ± 6.91 | 0.001 | 91.4 ± 10.70 | 80.5 ± 6.66 | 0.002 |
| Nasofrontal angle (°) | 132.7 ± 9.10 | 144.0 ± 6.74 | <0.001 | 141.8 ± 5.68 | 148.1 ± 5.12 | 0.002 |
| Columella-labial angle (°) | 90.1 ± 11.91 | 97.9 ± 7.85 | 0.012 | 101.4 ± 8.60 | 103.6 ± 6.23 | 0.416 |
| LIP-RELATED INDEXES | ||||||
| Upper vermilion height (mm) | 11.8 ± 2.30 | 9.5 ± 1.97 | 0.001 | 10.9 ± 1.09 | 8.3 ± 0.90 | <0.001 |
| Lower vermilion height (mm) | 13.5 ± 2.29 | 8.9 ± 1.81 | <0.001 | 11.5 ± 1.91 | 8.3 ± 0.99 | <0.001 |
| Vermilion height (mm) | 25.3 ± 3.84 | 18.3 ± 3.41 | <0.001 | 22.5 ± 2.46 | 16.5 ± 1.54 | <0.001 |
| BONE-RELATED INDEXES | ||||||
| Morphological face length (mm) | 136.6 ± 7.26 | 122.2 ± 7.80 | <0.001 | 122.5 ± 6.34 | 113.8 ± 4.30 | <0.001 |
| Face breadth (mm) | 144.5 ± 7.07 | 127.7 ± 7.80 | <0.001 | 130.3 ± 9.77 | 125.4 ± 6.41 | 0.102 |
| Facial length index (%) | 94.6 ± 4.83 | 95.9 ± 6.44 | 0.454 | 94.5 ± 8.55 | 91.0 ± 5.89 | 0.180 |
| Gonion-gnathion distance (mm) | 117.8 ± 7.90 | 112.0 ± 7.24 | 0.012 | 110.3 ± 6.60 | 103.9 ± 6.89 | 0.012 |
P1 indicates the difference between male patients and healthy males; P2 indicates the difference between female patients and healthy females; p < 0.05 means the difference is significant.