Table 2.

Diagnostic efficiency of models in differentiating NSCLC from the healthy controls.

	AUC (95% CI)	Sensitivity	Specificity	PPV	NPV
NSCLC vs. Healthy
PRL	0.818 (0.733, 0.904)	0.727	0.750	0.744	0.733
CEA	0.871 (0.789, 0.953)	0.772	0.932	0.919	0.804
CYFRA21	0.813 (0.717, 0.909)	0.750	0.819	0.805	0.766
PRL+CEA	0.942 (0.889, 0.994)	0.909	0.909	0.909	0.909
PRL+CYFRA21	0.880 (0.810, 0.950)	0.863	0.727	0.760	0.842
CEA+CYFRA21	0.926 (0.865, 0.987)	0.909	0.864	0.870	0.905
PRL+CEA+CYFRA21	0.960 (0.921, 0.999)	0.909	0.955	0.952	0.913

PPV, positive predictive value; NPV, negative predictive value.