Figure 3.
Effect of AT-312 on cocaine-induced CPP in wild-type (Upper; n = 13 mice per treatment) or knockout (Lower; n = 10 mice per treatment) mice. Data are mean (±SEM) of the amount of time that mice spent in the vehicle-paired chamber (VPCh) and drug-paired chamber (DPCh) on the preconditioning (D1) and postconditioning (D5) test days. **P < 0.01; ****P < 0.0001, a significant increase in the amount of time that mice spent in the DPCh vs. its respective VPCh on D5.