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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Shock. 2019 Jan;51(1):4–9. doi: 10.1097/SHK.0000000000001164

Table 5.

Examples of organ injury and immune dysfunction parameters. This table provides examples of parameters that would be appropriate to measure to document organ injury or dysregulated response to infection.

Organ Injury

  • Pulmonary injury

  • Liver injury

  • Kidney injury

  • Hematology changes

  • CNS alterations

Dysregulated host response to infection

  • Plasma biomarkers, i.e. IL-6

  • Complete blood count with differential

  • Temperature measurements

  • Blood and peritoneal cultures at time of sacrifice when humane criteria are met

Frequency of measurements

  • Daily

  • # of days