Table 1. Geriatric Assessment Domains, Definitions, and Importance.

Domain	Definitions	Importance
Comorbidities	Mention of chronic illnesses not including cancer.	Comorbidities are associated with poorer overall survival and poor treatment tolerance.
Polypharmacy	Mention of other OTC or prescription drugs.	Polypharmacy increases the risk of drug-drug interactions.
Nutrition	Mention of weight, appetite, eating, oral health.	Poor nutritional status is associated with increased need for functional assistance and poorer survival. Unintentional weight loss 6 months before chemotherapy is associated with lower chemotherapy response rates and lower overall survival.
Physical performance	Mention of exercise, mobility, strength, falls.	Falls are predictive of worse outcomes.
Functional status	Mention of ADLs or IADLs.	Poor functional status is predictive of chemotherapy toxicity and lower survival.
Social support	Mention of instrumental (e.g., financial, transportation) or emotional support.	Poor social support could impact adherence to treatment and decrease quality of life.
Cognition	Mention of ability to make decisions, memory issues, or confusion.	Poor cognition can influence adherence to treatment, understanding of the risks and benefits of treatment, and the ability to make decisions.
Mental health	Mention of mood, depression, or anxiety.	Psychological distress can influence patients’ physical performance.

Note. OTC = over the counter; ADLs = activity of daily living; IADLs = independent activity of daily living.