. 2018 Nov 16;33(50):e319. doi: 10.3346/jkms.2018.33.e319

Table 1. Clinical features of 4 SFTS patients retrospectively confirmed using stored blood samples collected during 2008–2013 in Korea.

Characteristics		Patient 1	Patient 2	Patient 3	Patient 4
Age, yr		62	49	57	21
Sex		Male	Male	Male	Male
Year of presentation		2008	2008	2012	2012
Outdoor activity		+	+	+	Unknown
Clinical findings
	Fever^a	+	+	+	+
	Fatigue	+	+	+	−
	Headache	+	−	−	+
	Abdominal pain	−	−	−	−
	Nausea or vomiting	+	+	+	+
	Diarrhea	+	+	+	+
	Bleeding tendency	−	−	−	−
	Splenomegaly^a	+	+	+	+
Laboratory findings
	Leukopenia^a	+	+	+	+
	Anemia^a	−	−	−	−
	Thrombocytopenia^a	+	+	+	+
	Elevated aminotransferases	+	+	+	+
	Elevated LDH	+	+	+	+
	Elevated ferritin^a	+	+	+	+
	Hypertriglyceridemia^a	+	+	−	+
	Hypofibrinogenemia^a	−	−	−	+
	Elevated IL-2 receptor alpha^a	+	+	+	+
	Hemophagocytosis in bone marrow^a	+	+	+	+
Treatment
	Antibiotics only	+	+	−	−
	HLH-specific agents^b	−	−	+	+
Outcome		Survived	Survived	Died	Survived

SFTS = severe fever with thrombocytopenia syndrome, LDH = lactate dehydrogenase, IL = interleukin, HLH = hemophagocytic lymphohistiocytosis.

^aDiagnostic criteria for HLH; ^bEtoposide, dexamethasone, and intravenous immunoglobulin.