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. 2018 Nov 29;9:1394. doi: 10.3389/fphar.2018.01394

Table 4.

Selective complication of agencies applying the RUCAM scale for causality assessment in suspected HILI.

Products Country Cases (n) Reference
Various herbal TCM Singapore 15 (Wai, 2006)
Black cohosh Spain 44 (European Medicines Agency [EMA], 2007)
Herbs Korea 13 (García-Cortés et al., 2008)
Various herbal TCM Korea 159 (Kang et al., 2008)
Polygonum multiflorum Korea 25 (Jung et al., 2011)
Various herbal TCM Hong Kong 45 (Chau et al., 2011)
Natural herbal products Various countries 73 (Bjornsson et al., 2012)
Various herbal TCM Spain 15 (Robles-Diaz et al., 2015)
Kava various countries 67 (Hardeman et al., 2008; Teschke et al., 2012)
Greater Celandine various countries 21 (Teschke and Lebot, 2011)