TABLE 1.
Enriched Gene Ontology terms in the smooth-33 mutanta
| GO term | FDR |
|---|---|
| Upregulated in the smooth-33 mutant | |
| DNA repair | 1.2E−05 |
| Regulation of transcription from RNA polymerase II promoter | 5.7E−04 |
| DNA recombination | 5.8E−03 |
| DNA replication initiation | 1.7E−02 |
| Cell cycle process | 3.3E−02 |
| Mismatched DNA binding | 3.3E−02 |
| Nucleosome assembly | 4.2E−02 |
| Downregulated in the smooth-33 mutant | |
| Small-GTPase-mediated signal transduction | 1.8E−03 |
| Steroid biosynthetic process | 4.0E−03 |
| GTP catabolic process | 4.9E−03 |
| Cytokinesis | 1.7E−02 |
| Nucleocytoplasmic transport | 2.7E−02 |
| Cellular lipid metabolic process | 3.5E−02 |
| Oxygen transport | 3.6E−02 |
| Membrane raft organization | 3.6E−02 |
| Chitin metabolic process | 4.2E−02 |
| Response to toxic substance | 4.2E−02 |
| Regulation of molecular function | 4.5E−02 |
| Fungal-type cell wall organization | 4.5E−02 |
| Microtubule-based movement | 4.9E−02 |
a
Analysis of the top 1,000 up- and downregulated genes identified biological process Gene Ontology (GO) terms specifically overrepresented in the smooth-33 mutant (false-discovery rate [FDR] of <0.01).