TABLE 3.
High-confidence genes involved in yeast-to-hyphae transitiona
| JGI protein ID | S. cerevisiae BlastPb | No. of strains | Predicted mutations recovered |
|---|---|---|---|
| 113409 | sln1 (nik1) | 5 | E342G, S441T, I536M, G584S, M598K |
| 140296 | cts1 | 4 | K2*, W134*, G285E, G284V/E837D |
| 127631 | ssk2 | 3 | G1190D, P555H, R526P |
| 109080 | sln1 (chk1) | 2 | T1290M, E1415K |
| 122144 | pbs2 | 2 | 2 x G371R |
| 124736 | hog1 | 1 | S335* |
| 128138 | hym1 | 1 | L103P |
| 131882 | lrg1 | 1 | G938C |
| 129277 | mih1 | 1 | Y476* |
a
Genes with mutations in independent mutant strains as well as genes found in only one strain but with few or no other nonsynonymous mutations. Eight mutant strains contained many nonsynonymous mutations in unique gene hits and are not shown.
b
Genes in parentheses represent the best BlastP hit from C. albicans.