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. 2018 Dec 5;3(6):e00427-18. doi: 10.1128/mSphere.00427-18

TABLE 4.

Definitions of meningococcal categories used in PCR analysesa

Category Isolate PCR Direct swab PCR WGS
All meningococci Any sample in which the porA and/or ctrA gene(s) was detected Any sample in which the porA and/or ctrA gene(s) and/or the group B capsule gene was detected Any sample in which the porA and/or ctrA sequences were predicted to encode full-length gene product
Grouped meningococci Any sample in which the porA and/or ctrA gene(s) and the relevant group capsule gene were detected Performed only for NmB Any sample in which the porA and/or ctrA sequences and all the required genes for synthesis and transport of the relevant capsule group were predicted to encode full-length gene products
Nongroupable meningococci Any sample in which the porA and/or ctrA gene(s) was detected but no capsule gene was detected Not applicable Any sample in which the porA and ctrA sequences were predicted to encode full-length gene product and lacking any of the required genes for synthesis and transport of the relevant capsule group OR any sample in which the ctrA sequence is incomplete
Non-NmB meningococci Not applicable Any sample in which the porA and/or ctrA gene(s) was detected but the group B capsule gene was not detected Not applicable
Group B meningococci See “Grouped meningococci” above Any sample in which the group B capsule gene was detected See “Grouped meningococci” above
a

Abbreviations: NmB, Neisseria meningitidis serogroup B; WGS, whole-genome sequencing.