Table 1.
Patient's serum biochemistry evolution and treatment protocol.
| Calcium | Phosphate | PTH* | ALP | 25(OH)D2 | 1,25(OH)2D3 | U Ca/cr (urine sample) | TmP/GFR | |
|---|---|---|---|---|---|---|---|---|
| Range | 2.2–2.54 mmol/L | 1.41–2.17 mmol/L | 15–65 ng/mL | 151–342 U/L | > 30 ng/mL | 20–80 pg/mL | <0.7 mmol/mmol | 1.04–2.79mmol/L |
| Baseline | 1.7 | 1.1 | 427 | 2,380 | 13 | 528 | 0 | 1.06 |
| FIRST PHASE TREATMENT | ||||||||
| 5,000 U vitamin D3 3,000 mg Ca/kg/d 1 month |
||||||||
| Start | 1.7 | 1.1 | 427 | 2,380 | 13 | 0 | 1.06 | |
| End | 1.69 | 1.09 | 574 | 2,132 | 37 | 0.19 | 1.43 | |
| SECOND PHASE TREATMENT | ||||||||
| iv calcium 45 mg/kg/d 4 months |
||||||||
| Start | 2.23 | 0.63 | 427 | 1,653 | 0.78 | 1.43 | ||
| End | 2.18 | 0.98 | 350 | 1,569 | 0.94 | 1.47 | ||
| THIRD PHASE TREATMENT | ||||||||
| Cinacalcet 0.27 mg/kg/d 2 months |
||||||||
| Start | 2.18 | 0.98 | 350 | 62 | 2.57 | 1.47 | ||
| End | 2.4 | 1.91 | 94 | 2.85 | ||||
| 6 months of follow-up | 2.33 | 1.51 | 23 | 304 | 2.15 | |||
PTH, parathyroid hormone,
measured by an electrochemiluminescence assay that detects full-length PTH (1–84). ALP, alkaline phosphatase. 25 (OH)D2, 25-hydroxyvitamin D; 1,25(OH)2D3, 1,25-dihydroxyvitamin D3; U Ca/cr, urinary calcium/creatinine ratio; TmP/GFR, tubular maximum reabsorption of phosphate per unit of glomerular filtrate; iv, intravenous.