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. 2018 Nov 28;6:376. doi: 10.3389/fped.2018.00376

Table 1.

Patient's serum biochemistry evolution and treatment protocol.

Calcium Phosphate PTH* ALP 25(OH)D2 1,25(OH)2D3 U Ca/cr (urine sample) TmP/GFR
Range 2.2–2.54 mmol/L 1.41–2.17 mmol/L 15–65 ng/mL 151–342 U/L > 30 ng/mL 20–80 pg/mL <0.7 mmol/mmol 1.04–2.79mmol/L
Baseline 1.7 1.1 427 2,380 13 528 0 1.06
FIRST PHASE TREATMENT
5,000 U vitamin D3 3,000 mg Ca/kg/d
1 month
Start 1.7 1.1 427 2,380 13 0 1.06
End 1.69 1.09 574 2,132 37 0.19 1.43
SECOND PHASE TREATMENT
iv calcium
45 mg/kg/d
4 months
Start 2.23 0.63 427 1,653 0.78 1.43
End 2.18 0.98 350 1,569 0.94 1.47
THIRD PHASE TREATMENT
Cinacalcet
0.27 mg/kg/d
2 months


Start 2.18 0.98 350 62 2.57 1.47
End 2.4 1.91 94 2.85
6 months of follow-up 2.33 1.51 23 304 2.15

PTH, parathyroid hormone,

*

measured by an electrochemiluminescence assay that detects full-length PTH (1–84). ALP, alkaline phosphatase. 25 (OH)D2, 25-hydroxyvitamin D; 1,25(OH)2D3, 1,25-dihydroxyvitamin D3; U Ca/cr, urinary calcium/creatinine ratio; TmP/GFR, tubular maximum reabsorption of phosphate per unit of glomerular filtrate; iv, intravenous.