Figure 13. Genomes with potential counter-defense systems.

Tweety gene 54 is active in counter defense against Phrann (see Figs. 11, 12), and there are homologues in many other Cluster F phages. The only phage outside of Cluster F with a closely-related homologue is the Subcluster A1 phage, Nerujay. All other Cluster A phages, including DD5, lack a Tweety 54 homologue. Segments of the genome maps are aligned with pairwise nucleotide sequence similarity shown as colored shading, as described for Figure 7. In this region, all of the DD5 and Nerujay genes are transcribed leftwards, and the Tweety genes are transcribed rightwards.