Table 2.

Mitochondrial respirometry performed on mitochondria isolated from liver tissue homogenates.

	High-fat
	Saline	MSC
Glutamate + Malate	2.4 ± 0.1	3.0 ± 0.5
ADP	22.4 ± 1.0	32.8 ± 3.8*
Oligomycin	2.6 ± 0.1	3.4 ± 0.5
RCR	9.4 ± 0.6	10.0 ± 1.0
Citrate synthase activity	15.5 ± 1.0	23.7 ± 1.1*

Basal oxygen consumption supported by glutamate and malate through complex I (Glutamate + Malate), maximal complex I oxygen consumption (ADP), oligomycin mediated proton leak (Oligomycin), and respiratory control ratio (RCR), a measure of mitochondrial oxidative coupling efficiency. Respirometric data was normalized to mg of mitochondrial protein. Data are mean ± SEM with n = 8 for both groups.

^*Denotes statistical significance at p < 0.05.