FIG 1.
Deletion of the hp0421 gene perturbs H. pylori cell morphology. (A to C) Confocal microscopy profiles depicting morphological patterns of the Hp76Δ421 (A), Hp76 (B), and Hp76Δ421-reconstituted (C) strains. (D) Scatter plots arraying Hp76wt, Hp76Δ421, and Hp76Δ421-reconstituted cells (recons) based on x-size and y-size analyses performed using CellTool software. (E) CellTool analysis output based on plots representing the distribution of Hp76wt, Hp76Δ421, and Hp76Δ421-reconstituted cell populations (recons) according to the aspect ratio. (F to H) Confocal microscopy images for Hp76Δ421 (F), Hp76 (G), and Hp76Δ421-reconstituted (H) cells when the cells were treated with the filamenting drug aztreonam.