TABLE 1.

MICs of wild-type, Δ421 mutants, and Δ421-reconstituted H. pylori strains

Antibiotic	MIC (μg/ml) of the following strain(s)a :
	Hp26695	Hp26695Δ421	Hp76	Hp76Δ421	Hp76Δ421- reconstituted
Fosfomycin	≥1,024 (R)	≤1.5 ± 0.5 (S)	≥1,024 (R)	≤0.064 ± 2 (S)	≥1,024 (R)
Colistin	≥256 (R)	≤12 ± 3 (S)	≥256 (R)	≤10 ± 5 (S)	≥256 (R)
Polymyxin B	≥256 (R)	≤8 ± 4 (S)	≥256 (R)	≤10 ± 4 (S)	≥256 (R)
Ciprofloxacin	≤0.38 ± 0.5 (R)	≤0.064 ± 0.02 (S)	≤0.50 ± 0.5 (R)	≤0.19 ± 0.2 (S)	≤0.047 ± 0.08 (R)
Tetracycline	≤10 ± 3 (R)	≤0.01 ± 0.02 (S)	≤0.50 ± 0.1 (R)	≤0.01 ± 0.09 (S)	≤0.38 ± 0.18 (R)
Amoxicillin	≤0.47 ± 0.01 (R)	≤0.016 ± 0.01 (S)	≤0.016 ± 0.01 (S)	≤0.016 ± 0.01 (S)	≤0.016 ± 0.01 (S)
Clarithromycin	≤0.001 (S)	≤0.001 (S)	≤0.001 (S)	≤0.001 (S)	≤0.001 (S)

^aThe letters in parentheses after the MICs indicate whether the strain is resistant (R) or sensitive (S) to the respective antibiotic.