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. 2018 Dec 6;16:228. doi: 10.1186/s12916-018-1213-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Impact of the annual HZ/su waning rate starting 4 years following vaccination on the threshold vaccine cost per series when using a a time horizon of 15 years or b a lifetime time horizon. The cost-effectiveness threshold was set at €20,000 per quality-adjusted life year gained. HZ, herpes zoster; HZ/su, herpes zoster subunit vaccine; VE, vaccine efficacy