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. 2018 Dec 6;16:228. doi: 10.1186/s12916-018-1213-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — One-way sensitivity analysis of HZ/su for vaccination of 70-year-olds. The threshold vaccine cost per series is the maximum cost to remain below a threshold of €20,000 per QALY gained. a Deterministic sensitivity analysis showing the impact of parameter uncertainty by using the lower (dark grey) and upper (light grey) ranges that were based on the 95% confidence intervals of the input parameters. b Scenario analysis showing the impact of structural uncertainty by using other plausible model inputs. GP, general practitioner; HC, healthcare; HCP, healthcare payer; HZ, herpes zoster; HZ/su, herpes zoster subunit vaccine; PHN, post-herpetic neuralgia; QALY, quality-adjusted life year; VE, vaccine efficacy