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. 2018 Dec 5;15:336. doi: 10.1186/s12974-018-1367-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — LAMP-1 protein level was increased 21 days after LPS exposure. LAMP-1 protein levels were measured by Western blot in the brain homogenates of rat pups injected with LPS (n = 8) and Sham (n = 8) 1 day (P4) and 21 days (P24) after injection, *p < 0.05 (a, b). LAMP-1 distribution in upper layers of somatosensory cortex (I–II) in neurons (NeuN-positive cells) (c) and microglia (ILB4-positive cells) (d) of LPS and Sham animals at P4 and P24 was analyzed by immunofluorescent confocal microscopy. Cortex I–II, cortical layers according to [64]