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. 2018 Dec 5;15:336. doi: 10.1186/s12974-018-1367-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — 21 days after LPS exposure, upper cortical neurons show reduced PSA immunostaining. a Neurons with decreased PSA immunostaining are detected in the upper somatosensory cortex (layers II–III) of LPS-injected rat pups at P24 (n = 3) after injections as compared to Sham animals (n = 3). PSA, green; neuronal marker NeuN, red. Bar graphs (b) show average PSA immunostaining intensity in cortical neurons counted for nine adjacent 0.0042-mm² sections of upper and lower layers of the somatosensory cortex. Bar represents 20 μm. ****p < 0.0001. n.s., non-significant, Cx, cortex; I–VI, cortical layers according to [64]