Table 2.
The discriminatory ability of the miRNA expression profile for the poor responsive and responsive groups
| A | ||
|---|---|---|
| miRNA | AUC | |
| Before radiation | After radiation | |
| miR-494-3p | 0.552 | 0.636 |
| let-7b-5p | 0.722 | 0.552 |
| miR-323a-3p | 0.562 | 0.512 |
| miR-19b-3p | 0.603 | 0.547 |
| miR-342-5p | 0.762 | 0.527 |
| miR-374a-5p | 0.568 | 0.625 |
| miR-519d | 0.658 | 0.647 |
| B | |
|---|---|
| miRNA ratio | AUC |
| Before radiation | |
| 130a-3p/let-7b-5p | 0.788 |
| 130a-3p/19b-3p | 0.763 |
| 130a-3p/374a-5p | 0.763 |
| 130a-3p/17-5p | 0.745 |
| 106a-5p/130a-3p | 0.732 |
| After radiation | |
| 130a-3p/let-7b-5p | 0.752 |
| 628-5p/let-7b-5p | 0.714 |
| 130a-3p/148a-3p | 0.686 |
| 148a-3p/494-3p | 0.676 |
| 148a-3p/628-5p | 0.671 |
The expression of 22 candidate miRNAs were changed to the ratio form to eliminate normalization issue in plasma. The top five miRNA ratios were statistically calculated their AUC values by ROC analysis form (A) before radiation group and (B) after radiation group