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. 2018 Dec 5;16:340. doi: 10.1186/s12967-018-1714-1

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Effect of DTX on tumor necrosis in rat EOCs. Microscopic pictures (HRF × 200) on day 0 (a), day 3 (b), day 7 (c), day 14 (d), and day 21 (e) of the histopathology of EOC specimens (A), which are demonstrated as spotty or patchy necrosis scattering in the tumor, were analyzed. Tumor necrosis was increased in the sensitive group but showed no remarkable change in the insensitive or control group. On days 14 and 21, tumor necrosis (B) was significantly different among the three groups, except for that in the insensitive vs. control group. p < 0.05, ^a: sensitive vs. control; ^b: sensitive vs. insensitive