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. 2018 Oct 17;301(10):1628–1637. doi: 10.1002/ar.23918

Figure 2.

Figure 2

Ibuprofen induces neurite growth on monolayer crude prep DRG neurons. Significant increases in neurite length were seen with 10 μM and 100 μM doses of ibuprofen, however, all doses increased neurite growth when compared to no drug control (shown by dotted line) and 100 μM GW9662 (shown in red) after 72 hr exposure (a). Fluorescence micrographs of the cultures show neurite length with no drug treatment (b), and 100 μM ibuprofen (c). Cultures were immunostained to detect β‐III tubulin (green). N = 6, mean ± SEM for each condition One‐way ANOVA with Dunnett's post hoc test, **P < 0.01.