Figure 7.

Berberine and metformin induced glycolysis in C2C12 myotubes. After preincubation with 5.6 mM (A,D), 15 mM (B,E), or 30 mM (C,F) glucose for 24 hours, the C2C12 cells were treated with berberine or metformin plus moderate glucose concentration (15 mM) overnight. Then glucose consumption (A‐C) and lactate release (D‐F) were measured. Data are expressed as mean ± SEM; **P < 0.01 and ***P < 0.001 versus corresponding control (without berberine or metformin treatment). SEM, standard error of mean