Table 2.
Initial and worst subsequent pathologic diagnoses for patients who did not undergo LEEP
| Exposed to Proflavine and did not Undergo LEEP (n = 108/232, 47%) | Not Exposed to Proflavine and did not Undergo LEEP (n = 64/160, 40%) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Worst Subsequent Pathologic Diagnosis | Worst Subsequent Pathologic Diagnosis | |||||||||||||
| Normal Colposcopy/No Biopsy(%) | NIL (%) | CIN 1 (%) | CIN 2/3 (%) | AIS (%) | Invasive Cancer (%) | Total (%) | Normal Colposcopy/No Biopsy (%) | NIL (%) | CIN 1 (%) | CIN 2/3 (%) | AIS (%) | Invasive Cancer (%) | Total (%) | |
| Initial Pathologic Diagnosis | ||||||||||||||
| NIL | 10 (9) | 2 (2) | 5 (5) | 0 (0) | 0 (0) | 0 (0) | 17 (16) | 17 (27) | 7 (11) | 4 (6) | 0 (0) | 0 (0) | 0 (0) | 28 (44) |
| CIN 1 | 45 (42) | 12 (11) | 28 (26) | 0 (0) | 0 (0) | 0 (0) | 85 (79) | 19 (30) | 2 (3) | 7 (11) | 1 (2) | 0 (0) | 0 (0) | 29 (45) |
| CIN 2/3 | 1 (1) | 0 (0) | 2 (2) | 3 (3) | 0 (0) | 0 (0) | 6 (6) | 1 (2) | 1 (2) | 1 (2) | 4 (6) | 0 (0) | 0 (0) | 7 (11) |
| AIS | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Total | 56 (52) | 14 (13) | 35 (32) | 3 (3) | 0 (0) | 0 (0) | 108 (100) | 37 (58) | 10 (16) | 12 (19) | 5 (8) | 0 (0) | 0 (0) | 64 (100) |
, Cases where subsequent pathology was equal to initial; 
, Cases where subsequent pathology was worse than initial. Normal Colposcopy/No Biopsy = Follow‐up colposcopy examinations were normal and did not require additional biopsies; NIL = Negative for Intraepithelial Lesion (normal, inflammation, hyperplasia and metaplasia); CIN 1 = Cervical Intraepithelial Neoplasia Grade 1; CIN 2/3 = Cervical Intraepithelial Neoplasia Grades 2, 3 and 2/3; AIS = Adenocarcinoma In‐situ; Invasive Cancer = Invasive adenocarcinoma.