Table 3.
Initial and worst subsequent pathologic diagnoses for patients who underwent LEEP
| Exposed to Proflavine and Underwent LEEP (%)(n = 124/232, 53%) | Not Exposed to Proflavine and Underwent LEEP (%)(n = 96/160, 60%) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Worst Subsequent Pathologic Diagnosis | Worst Subsequent Pathologic Diagnosis | |||||||||||||
| Normal Colposcopy/No Biopsy(%) | NIL (%) | CIN 1 (%) | CIN 2/3 (%) | AIS (%) | Invasive Cancer (%) | Total (%) | Normal Colposcopy/No Biopsy (%) | NIL (%) | CIN 1 (%) | CIN 2/3 (%) | AIS (%) | Invasive Cancer (%) | Total (%) | |
| Initial Pathologic Diagnosis | ||||||||||||||
| NIL | 0 (0) | 1 (1) | 0 (0) | 6 (5) | 0 (0) | 0 (0) | 7 (6) | 0 (0) | 0 (0) | 3 (3) | 4 (4) | 0 (0) | 1 (1) | 8 (8) |
| CIN 1 | 0 (0) | 0 (0) | 7 (6) | 9 (7) | 0 (0) | 0 (0) | 16 (13) | 0 (0) | 0 (0) | 3 (3) | 9 (9) | 0 (0) | 0 (0) | 12 (13) |
| CIN 2/3 | 0 (0) | 8 (6) | 11 (9) | 81 (65) | 0 (0) | 0 (0) | 100 (81) | 0 (0) | 5 (5) | 8 (8) | 63 (66) | 0 (0) | 0 (0) | 76 (79) |
| AIS | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (1) | 1 (1) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Total | 0 (0) | 9 (7) | 18 (15) | 96 (77) | 0 (0) | 1 (1) | 124 (100) | 0 (0) | 5 (5) | 14 (15) | 76 (79) | 0 (0) | 1 (1) | 96 (100) |
, Cases where subsequent pathology was equal to initial; 
, Cases where subsequent pathology was worse than initial; Normal Colposcopy/No Biopsy = Follow‐up colposcopy examinations were normal and did not require additional biopsies; NIL = Negative for Intraepithelial Lesion (normal, inflammation, hyperplasia and metaplasia); CIN 1 = Cervical Intraepithelial Neoplasia Grade 1; CIN 2/3 = Cervical Intraepithelial Neoplasia Grades 2, 3 and 2/3; AIS = Adenocarcinoma In‐situ; Invasive Cancer = Invasive adenocarincoma.