Table 4.
Summary of cases where subsequent pathologic diagnosis was worse than baseline diagnosis
| All Patients | Did Not Undergo LEEP | Underwent LEEP | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Initial Diagnosis | Worst Subsequent Diagnosis | Proflavine Exposure (n = 232) (%) | No Exposure (n = 160) (%) | P‐valuea | Proflavine Exposure (n = 108) (%) | No Exposure (n = 64) (%) | P‐value | Proflavine Exposure (n = 124) (%) | No Exposure (n = 96) (%) | P‐value |
| NIL | CIN 1 | 5 (2.2) | 7 (4.4) | 0.19 | 5 (4.6) | 4 (6.3) | 0.50 | 0 (0) | 3 (3.1) | 0.35 |
| NIL | CIN 2/3 | 6 (2.6) | 4 (2.5) | 0 (0) | 0 (0) | 6 (4.8) | 4 (4.2) | |||
| CIN 1 | CIN 2/3 | 9 (3.9) | 10 (6.3) | 0 (0) | 1 (1.6) | 9 (7.3) | 9 (9.4) | |||
| NIL | Invasive Cancer | 0 (0) | 1 (0.6) | 0 (0) | 0 (0) | 0 (0) | 1 (1.0) | |||
| AIS | Invasive Cancer | 1 (0.4) | 0 (0) | 0 (0) | 0 (0) | 1 (0.8) | 0 (0) | |||
| Total | 21 (9.1) | 22 (13.8) | 5 (4.6) | 5 (7.8) | 16 (12.9) | 17 (17.7) | ||||
a
P‐values calculated using Fisher's exact test based on total cases where subsequent diagnosis was worse than initial.