Figure 1.

DNP upregulates miR‐149 expression. A, Structure of DNP, a N‐nitroso compound. B, miRNA sequencing was used to construct miRNAs expression profiles of DNP‐treated 6‐10B cells and the untreated. Red represents high expression, and green is low expression. C, miR‐149 was detected using qRT‐PCR in 6‐10B cells treated with DNP and the untreated cells, and 5‐8F cells served as a positive control. D, The expression of miR‐149 was detected in the tumors and paired adjacent tissues from NPC patients. DNP, Dinitrosopiperazine. *P < 0.05