. Author manuscript; available in PMC: 2018 Dec 6.

Published in final edited form as: J Dev Orig Health Dis. 2017 May 9;8(5):575–583. doi: 10.1017/S2040174417000290

Table 2.

Comparison of gene expression in hypodermis in the subsample with higher birth weight versus control

Gene	Average Gene Expression Control ^a	Average Gene Expression Increased Birth Weight ^b	Fold Change ^c	Unadjusted P value ^d	FDR Adjusted P Value ^e
PAI-1	20.4 ± 1.8	66.6 ± 31.7	3.27	0.0011	0.0198
GLUT4	27.6 ± 1.6	50.2 ± 7.9	1.82	<0.0001	0.0022
LEPR	83.3 ± 3.8	145.6 ± 21.8	1.75	<0.0001	0.0010
LPL	15.3 ± 0.9	24.6 ± 5.4	1.61	0.0038	0.0429
MMP2	348.8 ± 22.3	558.9 ± 74.6	1.60	0.0013	0.0198
IRS2	50.8 ± 2.3	75.9 ± 10.7	1.50	0.0007	0.0159
LRP1	318.1 ± 10.0	443.8 ± 29.5	1.39	0.0044	0.0439
TCF7L2	156.1 ± 5.9	201.6 ± 15.7	1.29	0.0053	0.0474
HDAC1	434.5 ± 9.6	344.7 ± 15.4	0.79	0.0004	0.0120
TXN	3095.9 ± 144.8	2221.7 ± 178.6	0.72	0.0017	0.0213

Data are given as mean ± SEM,

Increased birth weight group is the top 15 percent from the study (n = 7) compared to the rest (n = 40),

Fold change in mean gene expression of increased birth weight divided by control,

Unadjusted p-values from t-tests are shown.

False discovery rate-adjusted p-values are displayed; since this table includes only genes with FDR-adjusted p-values below 0.05, the interpretation is that we expect 9 or 10 of these discoveries to be true.