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. Author manuscript; available in PMC: 2018 Dec 6.
Published in final edited form as: Cell Rep. 2018 May 29;23(9):2795–2804. doi: 10.1016/j.celrep.2018.04.096

Figure 5. HDX-MS analysis of CP, comparing CARMIL CBR115-bound CP with free CP.

Figure 5.

A cartoon representation of CARMIL CBR115-bound CP is shown, based on PDB 3LK3 (Hernandez-Valladares et al., 2010). CARMIL CBR115 is shown as green surface, with its unresolved residues 1005-1020 between CPI and CSI motifs modeled and C-terminal residues 1034-1078 indicated as a dashed line. Differences in deuterium uptake induced by CARMIL CBR115 binding are displayed as a color gradient (see scale at bottom). Representative comparison of deuterium uptake curves of CP (black) and CARMIL CBR115-bound CP (blue) are shown on the right. These data are representative of two independent experiments. See also Figure S6 and S7.