Table 1.

Contractile Parameters for CMPs at SL 2.1 μm

	Ctrl	HCM	Ctrl+Bep
${\mathbf{F}}_{\mathbf{max}}\left(\frac{\mathbf{m}\mathbf{N}}{\mathbf{m}{\mathbf{m}}^{\mathbf{2}}}\right)$	42.6 ± 3.3	36.7 ± 2.6	39.2 ± 5.0
FpCa50	5.57 ± 0.02	6.18 ± 0.03*,#	5.77 ± 0.04*
nHill	3.0 ± 0.2	2.4 ± 0.4*	1.9 ± 0.2*
ktr max (s−1)	19.3 ± 1.1	24.8 ± 0.9*,#	27.8 ± 1.0*
SSmax (MPa)	2.3 ± 0.3	1.4 ± 0.1*	2.2 ± 0.4
SSpCa50	5.59 ± 0.02	6.28 ± 0.03*,#	5.81 ± 0.04*

F_max = maximum steady-state isometric force; F_pCa50 = pCa needed to reach 50% of the maximum steady-state isometric force; n_Hill = cooperativity of thin filament activation; k_{tr max} = maximum rate of tension redevelopment; SS_max = maximum steady-state sinusoidal stiffness; SS_pCa50 = pCa needed to reach 50% of the maximum steady-state sinusoidal stiffness.

^*p<0.05, HCM or Ctrl+Bep vs. Ctrl

^#p<0.05, HCM vs. Ctrl+Bep

The statistical significance for F_max, F_pCa50, k_{tr max}, SS_pCa50 was determined using one-way ANOVA with post-hoc Student-Newman-Keuls test.

The statistical significance for n_Hill, SS_max was determined using Kruskal-Wallis one-way analysis of variance on ranks.

Number of CMPs = 10–23 per parameter.