Table 1.
Demographics and Baseline Characteristics
| BI 655064 | ||||||
|---|---|---|---|---|---|---|
| 80 mg (n = 8) | 120 mg (n = 8) | 180 mg (n = 8) | 240 mg (n = 8) | Placebo (n = 8) | Total (N = 40) | |
| Sex, n (%) | ||||||
| Male | 6 (75) | 8 (100) | 6 (75) | 7 (87.5) | 6 (75) | 33 (82.5) |
| Female | 2 (25) | 0 | 2 (25) | 1 (12.5) | 2 (25) | 7 (17.5) |
| Race, n (%) | ||||||
| White | 6 (75) | 7 (87.5) | 5 (62.5) | 6 (75) | 5 (62.5) | 29 (72.5) |
| Hawaiian/Pacific Islander | 0 | 0 | 3 (37.5) | 2 (25) | 2 (25) | 7 (17.5) |
| Asian | 2 (25) | 1 (12.5) | 0 | 0 | 1 (12.5) | 4 (10) |
| Mean age, years (SD) | 25.9 (4.1) | 31.4 (13.3) | 37.3 (10.8) | 29.5 (10.6) | 27.8 (12.1) | 30.4 (10.8) |
| Mean BMI, kg/m2 (SD) | 24.5 (2.0) | 24.4 (4.3) | 26.7 (2.4) | 24.2 (3.0) | 25.4 (3.1) | 25.0 (3.1) |
| Smoking history, n (%) | ||||||
| Never smoked | 7 (87.5) | 7 (87.5) | 6 (75) | 5 (62.5) | 7 (87.5) | 32 (80) |
| Ex‐smoker | 0 | 0 | 2 (25) | 0 | 0 | 2 (5) |
| Currently smokes | 1 (12.5) | 1 (12.5) | 0 | 3 (37.5) | 1 (12.5) | 6 (15) |
| Alcohol history, n (%) | ||||||
| Non‐drinker | 1 (12.5) | 2 (25) | 0 | 1 (12.5) | 1 (12.5) | 5 (12.5) |
| Drinkera | 7 (87.5) | 6 (75) | 8 (100) | 7 (87.5) | 7 (87.5) | 35 (87.5) |
BMI, body mass index; SD, standard deviation.
a
At a level that did not interfere with study participation, based on investigator assessment.