FIGURE 5.

Gut microbes signature of rearing environment and nutrient resources. Top 20 most predictive OTUs that differentiate SR (sow reared) from IR (isolated reared) in 20-day-old pigs. These OTUs were ranked by random forest based on their Mean Decrease Accuracy. Out-of-bag error rate was 0%. A single letter following OTU number indicates genus, which was classified against the Ribosomal Database Project. All OTUs except OTU15 Cloacibacillus were more abundant in IR pigs than SR pigs. Of the top 20 OTUs, those highlighted with yellow color were negatively correlated with day 20 Foxp3 Treg T cell population, and positively correlated with subsequent growth phenotypes, while those OTUs highlighted with green color were positive correlated with growth performance (see Supplementary Table S3 for details).