Table 3.
Univariate and multivariate linear regression analyses
| Dependent variable | Independent variables | Univariate analysis | Multivariate analysis | R 2 | ||||
|---|---|---|---|---|---|---|---|---|
| Beta | 95% CI (lower, upper) | P | Beta | 95% CI (lower, upper) | P | |||
| IFN‐gamma | Child‐Pugh score | −0.8 | (−1.5, −0.07) | .032 | −0.8 | (−1.4, −0.1) | .030 | |
| Bacterial DNA | 3.2 | (0.8, 5.5) | .009 | 1.3 | (−1.0, 3.9) | .249 | ||
| LPS | 4.9 | (0.9, 8.8) | .016 | 2.9 | (−0.7, 7.4) | .102 | ||
| Leukocytes | 5 × 10−4 | (5 × 10−5, 1 × 10−3) | .029 | 4 × 10−4 | (6 × 10−6, 9 × 10−4) | .050 | 0.19 | |
| IL10 | Bacterial DNA | 8.8 | (3.3, 14.3) | .002 | 5.5 | (−0.4, 11.4) | .065 | |
| LPS | 16.6 | (7.6, 25.6) | .001 | 12.7 | (2.9, 22.4) | .012 | 0.21 | |
| IL6 | NSBB | 15.3 | (1.0, 29.5) | .036 | 15.7 | (2.2, 29.2) | .023 | |
| Leukocytes | 3 × 10−3 | (4 × 10−5, 6 × 10−3) | .047 | 2 × 10−3 | (6 × 10−4, 5 × 10−3) | .118 | 0.19 | |
INF, interferon; LPS, gram‐negative bacterial endotoxin; NO, nitric oxide; NSBB, non‐selective beta‐blocker; TNF, tumour necrosis factor.
Univariate linear regression analyses were calculated to predict NO, TNF‐alpha, IFN‐gamma, IL10 or IL6 based on NSBB, bacterial DNA, LPS and variables shown in Table 1. Only significant variables in the univariate analysis were included in the multivariate analysis and are shown in the table.