Table 2.

Models with Genu FA as an Outcome versus WMH as an Outcome

Variable	Regression Coefficient (SE)	p
FA as an outcome
Intercept	−0.83 (0.10)	<0.0001
WMH	23.80 (2.60)	<0.0001
CMC	0.36 (0.13)	0.007
WMH*CMC	−7.97 (3.05)	0.009
WMH as an outcome
Intercept	0.03 (0.002)	<0.0001
FA score	0.023 (0.003)	<0.0001
CMC	0.004 (0.003)	0.216
FA score*CMC	−0.003 (0.003)	0.447

CMC = cardiovascular and metabolic conditions; FA = fractional anisotropy; WMH = white matter hyperintensities.