Table 2. Median values of uPA-PAI-1 complexes in subgroups according to clinical-pathological characteristics of the subjects (N=66). IQR: interquartile range. * statistically significant difference in mean values between groups.
| Variable | uPA-PAI-1 complex (median (IQR)) |
|---|---|
| Menopausal status | |
| Premenopausal | 1.37 (0.76) |
| Post-menopause | 1.35 (0.93) |
| Tumor size | |
| pT1 | 1.20 (1.08) |
| pT2 | 1.43 (0.88) |
| Histological grade | |
| G0 | N/A |
| G1 | 1.58 (1.12) |
| G2 | 1.40 (1.14) |
| G3 | 1.31 (0.77) |
| Histological type | |
| Invasive ductal cancer | 1.43 (0.86) |
| Invasive lobular cancer | 0.72 (0.74) |
| Other | 1.41 (1.26) |
| Status of axillary lymph nodes | |
| N0 | 1.37 (1.03) |
| N1 | 1.13 (0.63) |
| N2 | 1.64 (1.28) |
| N3 | 1.24 |
| Expression of estrogen receptors | |
| Positive | 1.36 (0.96) |
| Negative | 1.34 (0.55) |
| Expression of progesterone receptors | 1.20 (0.97) |
| Positive | 1.43 (0.66) |
| Negative | |
| HER-2 expression | * |
| Positive | 0.99 (0.64) |
| Negative | 1.44 (1.01) |
| Ki67 | |
| ≤20% | 1.43 (1.01) |
| >20% | 1.47 |
| Unknown | 1.32 (0.81) |
| Invasion of blood vessels | |
| Absent | 1.43 (1.10) |
| Present | 1.34 (0.80) |
| Neural invasion | |
| Absent | 1.35 (0.91) |
| Present | 1.39 (0.86) |