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. 2018 Aug 10;78(16):1299–1310. doi: 10.1002/pros.23703

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© 2018 The Authors. The Prostate Published by Wiley Periodicals, Inc.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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MCM10 knockdown inhibits cell proliferation in PCa cells. A‐B, The Celigo® system revealed that knockdown of MCM10 inhibited cell proliferation in DU145 (A) and PC‐3 (B) cells. C‐D, The cell counting show significant decrease in shMCM10 group compared to shCtrl group in DU145 (C) and PC‐3 (D) cells. E‐F, An MTT assay demonstrated that knockdown of MCM10 inhibited cell proliferation in DU145 (E) and PC‐3 (F) cells. Each experiment was performed in triplicate (n = 3). *P < 0.05; **P < 0.01; ***P < 0.001. MCM10, Minichromosome maintenance 10 replication initiation factor; Ctrl, control; OD, optical density; sh, short hairpin. [Color figure can be viewed at http://wileyonlinelibrary.com]