Figure 5.
MCM10 knockdown significantly reduced colony formation of prostate cancer cells. A, MCM10 knockdown significantly reduced colony formation of DU145 cells. B, Quantitative representation of the DU145 colony formation following MCM10 knockdown. C, MCM10 knockdown significantly reduced colony formation of PC‐3 cells. D, Quantitative representation of the PC‐3 colony formation following MCM10 knockdown. The results are presented as the mean ± standard deviation (n = 3). *P < 0.05; **P < 0.01; ***P < 0.001. MCM10, Minichromosome maintenance 10 replication initiation factor; Ctrl, control; PCa, prostate cancer; sh, short hairpin. [Color figure can be viewed at http://wileyonlinelibrary.com]