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. 2018 Aug 10;78(16):1299–1310. doi: 10.1002/pros.23703

Figure 8.

Figure 8

Knockdown of MCM10 regulates cell proliferation‐related genes in PC‐3. A, Heatmap showed expression levels of 30 MCM10 targets after MCM10 knockdown in PC‐3. B, Real‐time reverse transcription PCR analysis showed 13 genes were downregulated after MCM10 knockdown. C, Real‐time reverse transcription PCR analysis showed 15 genes were up‐regulated after MCM10 knockdown in PC‐3. The results are presented as the mean ± standard deviation (n = 3). *P < 0.05; **P < 0.01; ***P < 0.001. Ctrl, control; MCM10, minichromosome maintenance 10 replication initiation factor; PCa, prostate cancer; sh, short hairpin. [Color figure can be viewed at http://wileyonlinelibrary.com]