Figure 1.

Schematic representation of (top) bimodal peptide targeted lipopolyplexes formulated with a bimodal peptide consisting of an EGFR targeting sequence, a furin cleavable RVRR linker, a DNA condensing K₁₆ sequence, and (bottom) surface targeted lipopolyplexes formulated using an EGFR targeting sequence bioconjugated to the lipid bilayer, and a separate K₁₆ peptide to condense the DNA. The lipid, peptide, and plasmid DNA components used in these experiments are shown on the right hand side