Figure 2.

Dihydromyricetin (DHM) reduces NLRP3 inflammasome expression in APP/PS1 mice. A, Immunofluorescent images showing NLRP3 staining after 2 and 4 weeks of DHM treatment compared with control groups. Scale bars: 40 μm. B, C, Bar graphs showing quantification of NLRP3‐positive cells in each group. Values are presented as mean ± SEM (*P < .05, **P < .01, ***P < .001 vs control group). D‐G, Western blot analysis showing a significant reduction in NLRP3 protein in DHM‐treated mice relative to control groups