Figure 1.

Study design. eGFR, estimated glomerular filtration rate; q.d., once daily; SU, sulfonylurea; R, randomization.¹Subjects initiated dapagliflozin 5 mg q.d. at Randomization/Visit 3/Day 1 and were to uptitrated to dapagliflozin 10 mg q.d. at Visit 4/Week 4. ²The interval between Visit 1 and Visit 2 for eligible subjects was to be at least 2 weeks and no more than approximately 6 weeks. ³Subjects entering the study on metformin remained on a stable dose of metformin; subjects entering on metformin + an SU remained on stable doses of both agents