Table 3.

Univariate and multivariate analysis in patients with pNET

	Univariate analysis					Multivariate analysis
Factor	Size	CgB		CgA		Size	CgB		Size	CgA
		OR (95% CI)	P value	OR (95% CI)	P value		OR (95% CI)	P value		OR (95% CI)	P value
Age (years old)	91	0.98 (0.94–1.01)	0.16	1.02 (0.99–1.06)	0.25		–
Sex, male versus female	91	0.93 (0.39–2.4)	0.89	2.26 (0.81–6.35)	0.12		–
Functioning tumor, yes versus no	91	1.14 (0.47–2.96)	0.78	0.98 (0.35–2.70)	0.96		–
Primary tumor size more than 2 cm, yes versus no	62	3.6 (1.03–15.9)	0.048*	12.8 (1.56–104.9)	0.002*	61	1.79 (0.099–2.7)	0.47	56	4.43 (0.46–111.6)	0.21
Historical grade, G2 versus G1	83	2.17 (0.85–6.0)	0.12	2.72 (0.88–8.41)	0.07				56	4.20 (0.51–89.2)	0.19
Presence of MEN-1, yes versus no	91	0.81 (0.15–4.35)	0.79	2.08 (0.24–18.0)	0.51		–
Presence of liver metastases, yes versus no	91	4.29 (1.4–10.4)	0.003*	27.5 (3.49–217.2)	<0.0001*	61	4.20 (0.79–33.5)	0.10	56	866 066 5776.68-	0.0004*

OR, odds ratio; CI, confidence interval; variables with P < 0.1 (bold figure) in univariate analysis were retained in multivariate regression analysis (available-case analysis). *Statistically significant (P < 0.05); size, the number of the case excluded for missing data.